Morphine administration and abrupt cessation alter the behavioral diurnal activity pattern
نویسندگان
چکیده
منابع مشابه
Abrupt shift of the pattern of diurnal variation in stroke onset with daylight saving time transitions.
BACKGROUND Stroke onset shows a pattern of diurnal variation, with a peak in morning hours. Rhythmic changes in blood pressure, hormones, and other parameters have been suggested as underlying mechanisms, but exogenous factors such as increasing physical activity after awakening may also be of relevance. To characterize the impact of external clock changes on the rhythmic variation in stroke on...
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Repeated microinjections of morphine into the ventrolateral periaqueductal gray (vPAG) produce tolerance to the antinociceptive effect of morphine [Behav Neurosci 113 (1999) 833]. These results may be a direct effect of morphine on cells within the vPAG or be caused by cues linked to the microinjection procedure (i.e. associative tolerance). The objective of this paper was to determine whether ...
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Since Belgian law recently set a limit to morphine concentration detectable in blood and urine while driving a vehicle, questions arose about the implications for the medical use of opiates. We determined morphine concentrations in whole blood and urine by gas chromatography-mass spectrometry in 15 patients on continuous intrathecal morphine administration. Effects on blood and urine concentrat...
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AIMS To compare abrupt and gradual smoking cessation. DESIGN AND SETTING Randomized trial and observational study, Internet, 2007-2010. PARTICIPANTS Smokers with no strong preference for abrupt or gradual quitting were randomly assigned to quitting immediately (n=472), or to gradually reducing their cigarette consumption over 2 weeks and then quit (n=502). Smokers who strongly preferred to ...
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ژورنال
عنوان ژورنال: Pharmacology Biochemistry and Behavior
سال: 2012
ISSN: 0091-3057
DOI: 10.1016/j.pbb.2012.02.015